The attack came a day after Russia said it repelled a Ukrainian drone attack on Crimea, downing 36 of them over the peninsula.
"Air defence on duty intercepted and destroyed four Ukrainian missiles over the Crimea peninsula," the Russian defence ministry said.
Kyiv said it had hit the Saki airbase in western Crimea.
"Saki airfield! All targets have been shot!" Mykola Oleshchuk, Ukraine's air force commander, said on social media.
Ukraine has targeted Crimea, annexed by Russia in 2014, since the start of Moscow's full-scale offensive.
Kyiv said Friday that it had targeted a command post near Sevastopol on Thursday.
Russian occupational authorities in the eastern Donetsk region said Ukrainian shelling killed two people Saturday, the day before Moscow celebrates Orthodox Christmas.
"Two people were killed in Makiivka and Gorlovka," the Moscow-installed head of the Donetsk region, Denis Pushilin, said on Telegram, referring to two occupied eastern industrial towns.
Both sides have escalated attacks in recent days, as the conflict drags on into nearly two years.
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