Space Industry and Business News  
INTERN DAILY
New chemistry technique simplifies drug-making
by Brooks Hays
La Jolla, Calif. (UPI) Sep 1, 2016


disclaimer: image is for illustration purposes only

A team of researchers in China and the United States have found an easier way to turn chemicals into drugs.

One of the most difficult parts of drug synthesis is creating "one-handed" molecules. Most medical compounds involve chiral molecules, molecules that can exist in two forms -- as two mirror images, like a right hand and left hand.

Often, the mirror image of a medically beneficial chiral molecule can have adverse effects. But producing only the wanted form of a chiral molecule isn't easy.

The latest research simplifies the process.

Many drugs are built on beta-chiral centers. Beta-chiral centers are made by taking a beta methylene molecule -- a molecule with a carbon atom attached to two hydrogen atoms by single bonds -- and replacing one of the two hydrogen atoms with a new group of atoms, called a functional group.

The current method for this process is called conjugate addition, which requires the creation of a double bond between the carbon and functional group atoms.

Scientists have come up with a new way to break and replace the carbon-hydrogen bond using a palladium atom. The method offers a shortcut and reduces waste while ensuring proper chirality. The catalyst is much more precise in breaking the exact carbon-hydrogen bond.

"It is important to be able to synthesize only one of two mirror images of the molecule, and development of new catalytic methods that achieve this goal, starting with carbon-hydrogen bonds, is highly desired," Guosheng Liu, lead researcher and a professor at the Shanghai Institute of Organic Chemistry, explained in a news release.

The researchers shared their breakthrough in a new paper published in the journal Science.

"This new process provides an entirely new pathway for constructing one of the 'cornerstones' of chiral molecules, namely, beta-chiral centers, and should accelerate the development of chiral drugs," concluded Jin-Quan Yu, a professor of chemistry at the Scripps Research Institute.


Thanks for being here;
We need your help. The SpaceDaily news network continues to grow but revenues have never been harder to maintain.

With the rise of Ad Blockers, and Facebook - our traditional revenue sources via quality network advertising continues to decline. And unlike so many other news sites, we don't have a paywall - with those annoying usernames and passwords.

Our news coverage takes time and effort to publish 365 days a year.

If you find our news sites informative and useful then please consider becoming a regular supporter or for now make a one off contribution.
SpaceDaily Contributor
$5 Billed Once


credit card or paypal
SpaceDaily Monthly Supporter
$5 Billed Monthly


paypal only


.


Related Links
Hospital and Medical News at InternDaily.com






Comment on this article via your Facebook, Yahoo, AOL, Hotmail login.

Share this article via these popular social media networks
del.icio.usdel.icio.us DiggDigg RedditReddit GoogleGoogle

Previous Report
INTERN DAILY
Thyroid cancer 'epidemic' down to overdiagnosis: study
Paris (AFP) Aug 18, 2016
A reported epidemic of thyroid cancer in rich countries is in fact mainly due to overdiagnosis driven by new technologies, the UN's cancer research agency said Thursday. Up to 90 percent of the thyroid cancer cases diagnosed in recent decades are, instead, tumours that are "very unlikely" to cause any symptoms at all, let alone death, according to findings published in The New England Journa ... read more


INTERN DAILY
UNIST to engineer next-generation smart separator membranes

3-D-printed structures 'remember' their shapes

Berlin's IFA fair dons virtual reality headsets

New method developed for producing some metals

INTERN DAILY
The sky's no limit for young space professionals

Open Architecture opens opportunities for acquisition reform

Russia develops protected alternative to satellite communication

Two ViaSat network encryptors now NSA-certified

INTERN DAILY
Russian Carrier Rocket for Sea Launches Will Replace Ukraine's Zenit

Intelsat "doubles down" with Arianespace for an Ariane 5 dual success

Kourou busy with upcoming Arianespace missions

Ariane 5 is approved for this week's Arianespace launch with two Intelsat payloads

INTERN DAILY
Inferring urban travel patterns from cellphone data

India to Provide Cost Incentives to Use Homemade Version of GPS

Existing navigation data can help pilots avoid turbulence

Raytheon gets $52 million Miniature Airborne GPS task order

INTERN DAILY
First satellite-based wildlife monitoring tool for airports

Maiden flight for first Japanese F-35

Afghan air force gets more MD-530 helicopters

Lockheed Martin gets max $10B contract for Air Force C-130J production

INTERN DAILY
Continuous roll-process technology for transferring and packaging flexible LSI

Meteorite impact on a nano scale

Colors from darkness: Researchers develop alternative approach to quantum computing

Electrons at the speed limit

INTERN DAILY
Sentinel-1 provides new insight into Italy's earthquake

Quest to find the 'missing physics' at play in landslides

FLEX takes on mutants

LTU uses underground radar to locate post-Katrina damage

INTERN DAILY
Seabirds eat debris that looks like natural prey

Garbage crisis returns to parts of Lebanon

People enhanced the environment, not degraded it, over past 13,000 years

Microplastics found deep in the middle of the ocean









The content herein, unless otherwise known to be public domain, are Copyright 1995-2024 - Space Media Network. All websites are published in Australia and are solely subject to Australian law and governed by Fair Use principals for news reporting and research purposes. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA news reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. All articles labeled "by Staff Writers" include reports supplied to Space Media Network by industry news wires, PR agencies, corporate press officers and the like. Such articles are individually curated and edited by Space Media Network staff on the basis of the report's information value to our industry and professional readership. Advertising does not imply endorsement, agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. General Data Protection Regulation (GDPR) Statement Our advertisers use various cookies and the like to deliver the best ad banner available at one time. All network advertising suppliers have GDPR policies (Legitimate Interest) that conform with EU regulations for data collection. By using our websites you consent to cookie based advertising. If you do not agree with this then you must stop using the websites from May 25, 2018. Privacy Statement. Additional information can be found here at About Us.