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FLORA AND FAUNA
Intact 700-year-old virus found in caribou dung
by Brooks Hays
San Francisco (UPI) Oct 28, 2014


Google seeks way to search bodies for disease
San Francisco (AFP) Oct 28, 2014 - Google is exploring a way to search inside people's bodies for early signs of deadly illnesses such as cancer or heart disease.

A Life Sciences team at the special projects Google X Lab are experimenting with having "nanoparticles" hunt for signs of medical trouble in bloodstreams and then essentially report findings to sensors people could wear.

"This is still early-stage research, but we've done a number of promising experiments, so we're going to keep going," Google said in a description of the project made public Tuesday.

Imagined applications include a test for enzymes given off by arterial plaques that are about to rupture and cause a heart attack or stroke, or a way to watch for cancer cells after surgery or chemo treatments.

Early detection is known to dramatically increase chances of successfully treating a number of life-threatening diseases.

Batches of specially crafted nanoparticles, each microscopic in size, could be swallowed in pills and then absorbed into bloodstreams where they would stick to targeted cells such as cancer.

Magnetic qualities designed into nanoparticles allow them to be drawn to worn devices and counted using non-invasive detection methods such as light or radio waves, according to Google.

If successful, the technology could "help physicians detect a disease that's starting to develop in the body," the California-based technology titan said.

Google said that it would license the technology to companies interested in using it for medically approved diagnostics.

Google Life Sciences team innovations include contact lenses that measure glucose levels in tears to allow people with diabetes to track blood sugar, and eating utensils that cancel out trembling hands caused by diseases such as Parkinsons.

Google also last year formed a company called Calico with a mission to address problems of health and aging by harnessing advanced technologies.

Frozen caribou feces collected from the Selwyn mountains of Canada's Yukon and Northern Territories contained only fragments of its depositor's DNA. But the ice-cold poo did contain a 700-year-old virus -- a virus scientists were recently able to bring back to life.

"The DNA of viruses is preserved extremely well under cold conditions," Eric Delwart, a researcher at Blood Systems Research Institute in San Francisco, told NPR. Delwart led the team of researchers responsible for resurrecting the ancient virus.

Though only fragments of the caribou's DNA survived the many years of freezer burn, the virus's genetic material -- which likely lived in a plant before being eaten by the reindeer -- was much better protected, well-suited for a long stay inside a chunk of frozen dung.

"The find confirms that virus particles are very good 'time capsules' that preserve their core genomic material, making it likely that many prehistoric viruses are still infectious to plants, animals or humans," Jean-Michel Claverie, a researcher at Aix-Marseille University School of Medicine in France, told New Scientist. "This again calls for some caution before starting to drill and mine Arctic regions at industrial scales."

The oldest virus ever brought back to life dated back some 30,000 years; it was extracted from Siberian permafrost. Though 700 years may seem short in comparison, the caribou dung-sourced virus originates from a period of time rich in viruses that have since become eradicated. The newly resurrected virus is also a reminder of the reality of global warming -- a reality whereby long-frozen viruses may emerge from the thaw of a hotter climate.

"There's a theoretical risk of this, and we know that the nucleic acid of the virus was in great shape in our sample," Delwart told New Scientist. "But old viruses could only re-emerge if they have significant advantages over the countless perfect viruses we have at present."

The work of Delwart and his colleagues was published this week in the journal PNAS.


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FLORA AND FAUNA
African lion deserves 'endangered species' protection: US
Washington (AFP) Oct 27, 2014
Loss of habitat and prey are putting African lions in danger of extinction, and the majestic creatures need protection in order to save their species, the US government said Monday. "Following a review of the best available scientific information, the US Fish and Wildlife Service today proposed listing the African lion as threatened under the Endangered Species Act," the FWS said in a statem ... read more


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